Zoonose News–what’s happening with the latest bird flu?

I don’t know about you but when the last pandemic swept the globe, I got the distinct impression that beyond my family, nobody cared much about my health. Here in Iowa, masks were panned and mask mandates were banned. The unfortunate were ordered back to work. With that in mind, I decided to brush off my notes from the last round of bird flu and give them an update just in case this hits the fan. 

Perhaps you recall your biology and remember that a virus can’t reproduce on its own. It needs a host which was why lockdowns and masks were recommended during COVID.

Bird flu, H5N1, is an Influenza A (A as in Avian).

According to the CDC, Influenza A viruses are divided into subtypes based on two proteins on the surface of the virus: hemagglutinin (H) and neuraminidase (N). These are parts of the virus (which has a protein coat) that are easily identifiable—like IDing a perpetrator. If you want to read more about that here is a great description.  Let’s just say that it takes a matchup of the right H and N to allow a virus to invade your cells, hijack them, create “baby” viruses, and pop the cells to release more viruses. That is how we get the designations such as H1H1 (the deadly Swine flu) and H2N3 (another virulent strain.) Both of these, and all influenzas, are zoonoses–infections that can move between people and animals.

Viruses reproduce by injecting themselves into cells and replacing cellular RNA with their own. Influenza A, the type deadly to humans, has eight strands of RNA bundled together to give our poor cells a big punch.

Here is an old diagram showing Influenza A and the animals it traditionally infects. Note that H5N1is deadly to humans.

IIB-InfluVennZa-2018-1276x2-1

I’d like to thank https://informationisbeautiful.net/licensing for letting me use this for free because fewer than 100,000 people visit me here.

Many Type A viruses can creep between birds, humans, pigs, and now dairy cows. Birds are a significant reservoir of these viruses. Shore birds including geese are potent carriers, but other types of domestic and wild birds also carry viruses. For example, N3 viruses are associated with ducks.

Most Influenza A viruses originate in birds. However, not many of these are easily transmitted to people. They can be transmitted to pigs. Pigs are a common go-between for viruses. It’s known that pigs act as mixing vessels for bird flu which is hard for people to catch and pig flu which people can catch.  They create new types of flu inside them–possibly in their snouts/respiratory tracts. There are several other diseases that can be transmitted between pigs and people. Pigs and humans can infect each other with influenza more easily than birds and humans can infect each other. Pig flu symptoms are much like human flu symptoms.

Iowa is home to about 24 million hogs, with the number of hogs per farm on an ever-uphill climb. Iowa also has over 60 million chickens. What could go wrong?

We can’t directly blame the chickens. Domestic pigs get wild bird viruses when birds interact with water used for cleaning their housing facilities that sits on site in ponds. In my opinion, deregulation of such facilities is asking for a new flu to be created.

A new wrinkle is that the Influenza A virus is now being detected in dairy cows and catsDairy farms in Texas noticed that the cows were producing less milk, and thick milk, and all of the farm cats died. The cats are thought to have eaten infected birds or more likely unpasteurized milk. H5N1 has also been found in marine mammals and foxes.

A few people have gotten it, probably from air born particles laden with virus. Although the most recently infected person got a mild case from a cow, over half of humans infected with H5N1 die of respiratory illness. The good news is, it isn’t transmitted from one human to another, at least not yet. The main worry is that a mutation will allow this.

It is suspected that ground up chicken waste may have introduced the flu virus into dairy cattle. Did you know that dairy cattle in the US are fed “poultry litter” – a mix of poultry excreta, spilled feed, feathers, and other waste scraped from the floors of industrial chicken and turkey production plants? I sure didn’t! Besides being found in cattle and cats, this new bird flu breaks the global flu pattern where influenzas originate in Asia.

Now, Iowa will be welcoming even more cows to the state. And besides eating a diet of chicken scraps, dairy cattle are often shipped across the country, posing more of a threat of the spread of bird flu.

I’m remaining cautiously optimistic that once spring migration of wild birds is over, this flu will die down. I really don’t want to run on a wing and a prayer like we did during COVID. In the meantime, there are a few ways to get ahead of this potential pandemic.

1.     Cook eggs thoroughly. Make sure any chicken is cooked to an internal temperature of 165 degrees. The virus will denature and fall apart.

2.     Don’t let raw meat touch surfaces in your kitchen. Cook beef to at least 145 degrees. (Note: bird flu has not been found in non-dairy herds.)

3.     If cats can get the virus from unpasteurized milk, maybe you could too. Best avoid it. (Pasteurized milk has been found to contain virus particles.) 

4.     Move to California. Buy California products. California regulates the use of bird litter as food.

5.     If you use manure as fertilizer and it isn’t from a bag that reads “composted”, compost it. Please don’t use raw manure. It can burn plants and introduce pathogens.

6.     Wash hands and clothing after touching birds. You should also wear a facemask.

7.     Hunters should field dress birds while wearing protective equipment.

8.     Take an antiviral medication if you are sick after contact with infected animals. Bird flu symptoms in humans are similar to other flu symptoms: fever, fatigue, sore throat, muscle aches, vomiting, diarrhea, stuffy nose.

9.     Other states have taken steps such as killing infected birds and limiting cattle shipments.

10.  If you have pet birds, keep them in a covered location away from wild birds and wild bird droppings. Know the symptoms of bird flu: sudden death, nasal discharge, low appetite, limited egg production, soft or misshaped eggs, diarrhea, and un-coordination. It’s wild bird migration season so keep flocks inside and covered up.

The Secretary of Agriculture, Tom Vilsack, points out that cattle appear to be recovering from bird flu quite quickly. And no one has yet to become sick from consuming contaminated foods, at least as far as we know. Vaccines for cattle and humans (although we might not have enough) are being developed.

No doubt if COVID had affected farm animals, our governor might have taken it more seriously. She really was a dumb-dumb when it came to that virus. Or should I use the term bird brain?

Biden cares about your ED

Endocrine disruptors face government scrutiny

Unlike Trump, BIDEN CARES ABOUT YOUR ED

In an under the radar announcement, the EPA has decided to rebuild the endocrine disruptor screening program. I’m pretty happy about this. It’s an example of the kind of protection I expect from the government.

Endocrine systems, aka hormone systems, are found in all mammals, birds, fish, and many other animals. Hormones are chemical messengers and they regulate many biological processes.

 Here’s a cute poster of all of our hormones and what they do.

Many modern synthetic chemicals can act as hormones or interfere with their workings. Chemists have blessed us with over 85,000 synthetic chemicals. About 1000 of these are thought to be endocrine disruptors. These chemicals range in use from plasticizers to explosives. The EPA is the agency charged with testing and regulating these chemicals. Testing requirements began in 1998.  The idea was to make sure people and animals weren’t being exposed to disruptors. It stalled out and then stopped altogether in 2015. The program is one of those that doesn’t get funded, depending who is in charge of the government.  In particular, the EPA staff received little to no support and direction from the Trump Administration. 

Why would the average person care at all about endocrine disruption? 

Here are a few reasons: 

Endocrine disruptors, or EDs, can harm the thyroid. These chemicals can exhaust the thyroid, resulting in conditions such as obesity, heart problems, and insulin resistance. In fact, this harm can begin when a person is a small fetus– your mother’s exposure might give you obesity and fertility problems

Endocrine disruptors harm testicles, decreasing sperm function and testicular health. Being exposed to disruptors before birth can cause a short testicle to anus distance which is often associated with male infertility. They can also create hypospadias, in which the opening to the penis isn’t at the tip. 

They can cause ADHD which can be passed on to offspring, even grandchildren,  of people exposed.

Other problems which can result are cancer, including childhood, thyroid, breast, and prostate cancers along with decreased immune function, including a lowered response to vaccines.

The newly announced study focuses on endocrine disruptors found in pesticides. Since the year 2000, data from across the globe has been collected on people living in and near agricultural areas and those employed in agriculture and gardening. These populations experience high rates of birth defects, especially genital defects, along with higher rates of hormone dependent cancers, and poor semen quality.  Most prior studies have been epidemiological, meaning they look at overall health of populations. 

Although people living and working on and near farms bear a lot of pesticide exposure, people can get exposure from foods and manufacturing sites as well. The chemicals can get into air and water and travel long distances. Besides humans, wild animals are affected by endocrine disruptors. And epidemiological studies take years to complete which is why the new study is needed.  (Information comes from this source.)

The new study will systematically look at the pesticide chemicals themselves and screen them for endocrine disrupting properties.

Thirty pesticides will get added scrutiny in this project. The EPA has 403 pesticides to review in total and of this, 86 have enough data to be shown as not concerning. Additionally, 161 look to be safe from endocrine disrupting properties. This study will by no means forbid pesticide usage—it aims to do what the companies did not and test for safety of chemicals widely distributed in our environment. 

The screening tests mix cells with the possible endocrine disruptors and look for reactions between them. Often times, the chemicals being tested will fluoresce or change color when they interact. This new study will help look at pesticides and their by-products in an efficient way. Getting politicians to care enough to protect us will be a whole different challenge. Thankfully, the Biden administration has begun the process. 

(Photo below is from this test site.)

In order to keep us safe from synthetic chemicals, we need studies of their safety and most often the government, must do these studies. A color changing or fluorescence screening is an efficient way to look for Eds. 

Science News 2023: a dozen stories highlight the trivial and the profound

  1. German monks developed an easy to ship powdered beer. It’s environmentally friendly but at least for now, non-alcoholic.

   2. You get a pesky itch but your skin looks perfectly normal. Why?  Bacteria overgrowth may cause itching. A new study discovered Staphylococcus aureus can activate itch enzymes without causing inflammation.

    3. On a more serious note, a Sickle cell treatment has FDA approval.  The Sickle Cell mutation affects  hemoglobin and the blood’s ability to carry blood. It’s a painful, debilitating condition that shows up in adulthood. The new therapy is a gene editing technique and reverts red blood cells to their adolescent form. There is a catch for females. The treatment destroys egg cells and causes infertility.

    4. Vaccines have made the news more than once. An effective malaria vaccine is both safe and inexpensive. A new mRNA vaccine (the same type as the COVID vaccine) is being used to treat pancreatic cancer.  A vaccine to prevent RSV, respiratory syncytial virus, is now available to the public. Although it’s not new, studies have supported the safety and effectiveness about the HPV vaccine. Too bad Iowa schools have dropped teaching about it.

  5. If you are still soured on vaccines, even though the United States leads to world on COVID deaths, probiotics might ease COVID symptoms and enhance vaccine effectiveness in a variety of cases.

  6. Are you creeped out by public restrooms or bathrooms in general? A new silicone treatment creates a Slippery toilet bowl which repels bacteria.

   7. This past summer in the Northern Hemisphere was the hottest on record.

  8.  Iowa’s high cancer rate made the news. Our legislature’s response? To ban books.

 9. Plastic particles are everywhere, including in microwaved foods.

10. The year’s top extinctions– birds and mussels.

11. A new treatment for Muscular Dystrophy may make it a disease of the past. Children born with Duchenne Muscular Dystrophy, a genetic disease, lose muscle power until they are unable to breathe or pump blood effectively.

12. India is the first country to land a spacecraft on the Dark Side of the Moon.

What stories caught your attention?