The president’s COVID treatment seems to have worked, or so he claims.
At its heart, it was made from Designer antibodies from humans who have recovered from Covid and from mice who have been designed to have a human immune system.
What are antibodies? To understand them we need to review how viruses work.
Viruses are bits of genetic material that come in coatings that are covered with protein bits with a unique shape. These protein bits are called antigens. Antigens are how scientists identify viruses. They are like the calling card of a virus. Each one is unique to that type of virus. Technically anything that produces an immune response is an antigen. In COVID-19, the “spike protein” sticking out all over like a crown is considered the antigen. Proteins elicit an immune response, unlike the fatty lipid blob that contains the rest of the virus. The spike protein allows the virus to interact with our cells, penetrate them, and inject the viral material into our cells where it uses our cell mechanisms to reproduce itself. Yes, the viral infection is a lot like our cells getting raped and impregnated with a virus.
Antibodies may also be able to treat cancer. Image from cancer.gov
White blood cells recognize a virus as dangerous and cover the anitigens with antibodies to neutralize them. Other white blood cells can then eat the virus. Antibodies have to be tailored for each virus. Vaccines work by teaching white cells how to make the right antibody so they can leap into action without the learning curve. Keeping away from the virus and wearing a mask is like an abstinence only class while a vaccine is more like sex education with a pregnancy prevention compoenent.
In general, antibodies look like Ys under a microscope and you can buy antibody pins, lanyards, phone grips and facemasks. In the latter, the antibodies are shown with weapons–an axe, an arrow, and magic.
The president got a dose of these antibodies equal to three to four times the amount a human needs. Should the rest of us expect such treatment to be available soon? In a word, NO.
Supplies are limited because, in part, because Operation Warp Speed is more show than go when it comes to investment. Yes, it is a cheaply funded program which means most of us won’t able to afford this treatment.
The cost of monoclonals, especially for the higher doses needed for treatment, could split the world into the haves and have-nots. “It’s unlikely that that treatment will get down to a price point in the near future that it would be easily affordable globally,” says Seth Berkley, who leads Gavi, the Vaccine Alliance, and also heads an international COVID-19 vaccine effort.
A deadly virus which may cause sterility in males and a cure only available to some. Doctors are stuck saving the very person who got us into this mess, a man they condemn. I guess for most of us, it’s going to be abstinence only.